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Oxford Covid-19 vaccine Q&A: How efficient is it, and the way is it totally different to the Pfizer vaccine?

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The place is it being manufactured?

Whereas there are some doses coming from Europe within the very first occasion, the bulk shall be offered from the UK provide chain.

In an unique report on Jan 16, The Telegraph shared plans for a brand new £158m “super-factory”, which might produce 70m doses of an emergency vaccine on British soil- sufficient to vaccinate your complete nation towards new coronavirus strains inside 4 months. The manufacturing unit will open later this yr. 

Do you want two doses of the Oxford vaccine?

The MHRA has beneficial the over-18s ought to obtain two doses to be administered with an interval of between 4 and 12 weeks.

When will I get my second dose?

The Authorities introduced on Dec 30 that it was delaying the second dose of each vaccine in an effort to attain as many individuals as potential within the first spherical of vaccinations.

Each the Oxford vaccine and the Pfizer/BioNTech jab shall be given to folks as one shot, adopted by one other as much as 12 weeks later, in an effort to prolong some safety to as many individuals as potential as shortly as potential.

This isn’t with out controversy, nonetheless.

The federal government’s Joint Committee on Vaccination and Immunisation (JCVI) says unpublished knowledge suggests the Oxford-AstraZeneca vaccine remains to be efficient with doses 12 weeks aside – however Pfizer has stated it has examined its vaccine’s efficacy solely when the 2 doses got as much as 21 days aside.

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The World Well being Group has beneficial a spot of 4 weeks between doses – to be prolonged solely in distinctive circumstances to 6 weeks.

Will the vaccines be given out 24 hours a day?

In an additional bid to speed up vaccination, Boris Johnson has introduced that 24-hour vaccine centres shall be opened “as quickly as we will”, with the the pinnacle of NHS England confirming on Jan 17 that a number of hospitals will trial 24/7 vaccine centres throughout the subsequent ten days.

Matt Hancock, nonetheless, informed UKTN Breakfast a 24/7 method was unlikely to be “the most important issue” in hitting the mid-February goal, however he was “completely” behind it “if it helps velocity issues up”. 

Sources in Whitehall have stated that plans are in place to pilot a 24-hour vaccination centre to check demand. This comes as manufacturing firms have informed ministers that they won’t but be capable of produce sufficient vaccines ought to 24-hour roll out be launched throughout the nation. 

Supplying vaccinations in a single day will velocity up the rollout, and permit the Authorities to succeed in their objective of vaccinating 32 million people- 60 per cent of the UK grownup inhabitants by Spring-which was introduced on Jan 11. 

Can this vaccine assist the aged?

There have been considerations {that a} Covid-19 vaccine won’t work as properly on aged folks, very similar to the annual flu jab.

Nevertheless, knowledge from the Oxford/AstraZeneca trial suggests there have been “comparable” immune responses amongst youthful and older adults.

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The outcomes present that the vaccine is best tolerated in older folks in contrast with youthful adults, and produces an identical immune response in young and old adults.

Can pregnant ladies have the vaccine?

Pregnant ladies and breastfeeding moms have now been given the inexperienced gentle to take both the Oxford and Pfizer coronavirus vaccines following an acceptable case-by-case threat analysis with their healthcare practitioner.

It is a reversal of earlier recommendation which was put in place as precautionary measure.

Historically pregnant ladies are usually not included in scientific trials, however following a evaluate the MHRA are recommending pregnant ladies be given the chance to obtain the vaccine as as there isn’t a proof they might be in danger.

Dr June Raine, chief government of the MHRA, stated: “Our recommendation thus far has been that on condition that in preliminary lack of proof on a precautionary foundation, use of a vaccine wasn’t beneficial in being pregnant and girls with breastfeeding shouldn’t be given the vaccine.

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“However now that we have now reviewed additional knowledge that has turn into accessible, the Fee on Human medicines has suggested that the vaccine may be thought of to be used in being pregnant when the potential advantages outweigh the dangers following a person dialogue with each girl.”

Can folks with allergy symptoms have the vaccine?

The rollout of the Pfizer vaccine was quickly halted for those that are recognized to undergo from extreme allergic reactions following a handful of hostile occasions within the preliminary distribution of the vaccine. 

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There have been some considerations that this might additionally apply to the Oxford jab. 

Nevertheless, following a evaluate, the UK regulatory physique has beneficial each the Pfizer and Oxford vaccine are protected to manage to these with meals or medication allergy symptoms. 

Solely those that have a recognized historical past of reacting to vaccines prior to now ought to proceed with warning.

Sir Munir Pirmohamed, scientific pharmacologist and geneticist, and chairman of Fee on Human Drugs Professional Working Group, stated. “We have come to the advice folks with a recognized historical past of reacting to any particular elements of vaccine shouldn’t have it. However folks with allergy symptoms to different medicines or meals can have the vaccine.”

Dr June Raine added that “no less than 800,000 within the UK, in all probability 1,000,000 and a half within the US” have already obtained the Pfizer vaccine. 

There was “no further considerations and this offers us additional assurance that the chance of anaphylaxis may be managed by way of customary scientific steerage and an statement interval following vaccination of no less than quarter-hour.

Learn extra: The precedence record for the Oxford and Pfizer vaccines – and the way they are going to be rolled out

Have you ever had the Covid vaccine or are you as a consequence of get one? We need to hear from you. Get in contact with us right here.

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